Overview:

This session will delve into the safety and impact of various medications and therapeutics on breastfeeding mothers and their infants, using data-driven approaches to better understand their effects and implications for maternal and pediatric health.

Co-sponsor:

NIH/NICHD MRPINT Hub

Location:

Samuel H. Scripps Auditorium

Capacity:

250 attendees

Moderator:

Christina Chambers, PhD, MPH

9:00 AM

Introduction and Overview

Camille Fabiyi, PhD, MPH
Program Officer, Obstetric and Pediatric Pharmacology and Therapeutics Branch (OPPTB)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institutes of Health (NIH)

9:20 AM

Prevalence of exposure to medications during lactation, and use of electronic health records to study questions regarding medication/vaccine safety

Kristin Palmsten, ScD
Senior Research Investigator and Co-Director of the Pregnancy and Child Health Research Center
HealthPartners Institute, Minneapolis

9:40 AM

Mapping the Impact of Antibiotics on the Maternal-Infant Dyad

Shirley Tsunoda, PharmD
Professor and Associate Dean, Skaggs School of Pharmacy and Pharmaceutical Sciences
UC San Diego

10:00 AM

SSRI use during lactation and associations with HMOs and macronutrient alterations

Christina Chambers, PhD, MPH
Distinguished Professor, Department of Pediatrics
UC San Diego

10:20 AM

Ion Transporters in the Mammary Gland: From Lactation to Breast Cancer

Rajini Rao, PhD
Professor, Department of Physiology
Johns Hopkins University School of Medicine

10:40 AM

Weighing the Evidence: Ozempic in Human Milk

Kaytlin Krutsch, PhD, PharmD, MBA, BCPS
Director, InfantRisk Center of Excellence
Assistant Professor, Obstetrics and Gynecology
Texas Tech University Health Sciences Center School of Medicine

11:00 AM

Group Discussion
Advancing Maternal-Pediatric Therapeutics

Overview:

The first two weeks postpartum are a critical window for establishing milk production, including achievement of secretory activation and coming to volume (>500 mL of milk volume daily) to support ongoing lactation and achieve optimal infant feeding outcomes. This session will delve into new research on the identification, mitigation, and management of early, unplanned cessation of lactation in pump-dependent mothers and their infants in the neonatal intensive care unit (NICU). Data-driven, practical approaches will be provided that describe point-of-care measures, including mother’s own milk biomarkers of secretory activation, and “My Pumping Pathways,” a standardized and personalized approach for optimizing pumped milk volume in the first two weeks. This session will also describe methods to calculate the economic benefits and return on investment of optimizing mother’s own milk in the NICU.

Co-sponsor:

Medela

Location:

Breakout room 1

Capacity:

45 attendees

Speakers:

Leslie A Parker, PhD, APRN, FAANP, FAAN
Professor of Biobehavioral Nursing
College of Nursing
University of Florida

Clarisa Medina-Poeliniz, PhD, MSN, APN, CPNP
Post-Doctoral Fellow
University of Utah

Tricia J Johnson, PhD
Professor of Economics
Department of Health Systems Management
Rush University, Chicago

9:00 AM

Understanding and Preventing Early, Unplanned Lactation Cessation: An Integrated Framework
Leslie A Parker, PhD, APRN, FAANP, FAAN

9:20 AM

Biology of the First Two Weeks Postpartum and Point-of-Care Measures to Address Lactation Concerns
Clarisa Medina-Poeliniz, PhD, MSN, APN, CPNP

9:50 AM

Maternal Time, Milk Volume, and Opportunity Cost of Optimal Pumping Behaviors in First Two Postpartum Weeks
Tricia J Johnson, PhD

10:10 AM

Maternal Risk Factors for Early, Unplanned Lactation Cessation
Clarisa Medina-Poeliniz, PhD, MSN, APN, CPNP

10:30 AM

“My Pumping Pathways”: An Evidence-Based, Standardized and Personalized Approach for Breast Pump Use
Leslie A Parker, PhD, APRN, FAANP, FAAN

10:55 AM

Economic Impact: Calculating NICU Cost Savings of Mother’s Own Milk Feedings
Tricia J Johnson, PhD

11:15 AM

Group Discussion
Future Directions: Research Needs for Optimizing Mother’s Own Milk Feedings by Pump-Dependent Mothers

Overview:

This session will convene experts and thought leaders to discuss cutting-edge research and strategies for safeguarding human milk against emerging health threats. The goal is to collaboratively develop a white paper outlining enhanced surveillance strategies to ensure the safety and quality of human milk.

Location:

Breakout room 2

Capacity:

closed session

Participants:

will be announced shortly